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Coatings | Caladrix® Technology
Low-profile electrospun coatings and coverings for minimally invasive medical devices
The Caladrix® platform provides electrospun coatings and coverings on medical devices, textiles, meshes, stents, valves, frames and implants.
It helps device teams add functional surface performance – including permeability control, adhesion, flexibility and tissue interaction – while supporting the low-profile requirements of minimally invasive devices and delivery systems.
For cardiovascular, vascular and other implantable applications, Caladrix® coatings and coverings are designed with development, validation, scale-up and manufacturing in mind.
Demo implantable nitinol device with electrospun covering
Hybrid textile combining electrospun TPU onto a PET knit
Demo cardiovascular stent with electrospun covering
Hybrid textile combining electrospun PET with a PET weave
Demo vascular occluder device covered in electrospun TPU
Direct electrospun fibre deposition for coatings, coverings and hybrid structures
The Caladrix® platform uses electrospinning to deposit ultra-fine fibres directly onto or around medical device structures, including textiles, meshes, frames, stents, valves and implants. Electrospun materials can be applied as selective coatings, full coverings or multi-layer structures to support adhesion, encapsulation, permeability control, flexibility, surface behaviour and low-profile device coverage.
Beyond the coating itself, the platform enables device-specific engineering, tailoring materials around the device, its delivery system and the performance requirements it must meet throughout development, validation and scale-up.
Watch The Stent Cover Technology Video
Designed for devices where profile, delivery and coating performance matter
Minimally invasive devices often need coatings and coverings that add function without compromising profile, flexibility or deployment.
This reflects a wider shift in cardiovascular and minimally invasive device design: teams increasingly need coatings that add functionality without adding thickness to devices delivered through catheters.
In cardiovascular and vascular applications, coatings can influence how a device seals, handles, moves through a delivery system, interacts with tissue and performs after deployment.
The Caladrix® platform supports this by enabling thin, flexible electrospun coatings and coverings that can be engineered around permeability, adhesion, delamination risk, mechanical behaviour and device geometry.
This is especially relevant for heart valve textiles, covered stents, occlusion devices, vascular access devices, nitinol frames and catheter-delivered implants — where small changes in thickness, friction, permeability or coating integrity can affect development and performance.
What Caladrix® Enables
Electrospun coating performance engineered around the device
The Caladrix® platform enables coatings and coverings to be engineered around the performance requirements of the device, integrating functional electrospun architectures directly into the device design rather than treating the coating as a separate surface layer.
Low-profile coatings and targeted coverage
Create ultra-thin electrospun coatings, typically around <20–50 microns where application requirements allow, with the flexibility to apply fibres only where needed or create complete coverings and multi-layer device structures.
Permeability and interface performance
Tailor coating architecture to influence permeability, sealing behaviour and fluid transport while supporting robust integration with the underlying textile, mesh or implant structure to minimise delamination risk.
Flexible and durable mechanical behaviour
Engineer electrospun coatings that flex, conform and move with the device during manufacturing, delivery and clinical use while maintaining structural integrity and functional performance.
Device integration and simplified assembly
Support integration of electrospun fibres with device structures, enabling coating strategies that can reduce reliance on sutures or simplify assembly in suitable applications.
Hybrid textile and fibre architectures
Combine electrospun fibres with woven, knitted or mesh substrates to create hybrid materials that deliver both the mechanical strength of textiles and the functional benefits of electrospun fibre architectures.
Explore Caladrix® Applications
The Caladrix® platform is most relevant where medical device teams need low-profile coatings, coverings or hybrid structures that support permeability control, flexibility, adhesion and device delivery.
Cardiovascular
Low-profile electrospun coatings and coverings for heart valve textiles, covered stents, occlusion devices, vascular access devices, nitinol frames and catheter-delivered implants.
Orthopaedic
Mimetix® resorbable electrospun coating on a collagen membrane augmentation of tendon repair.
